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Irisin Protects Against Motor Dysfunction of Rats with Spinal Cord Injury via Adenosine 5'-Monophosphate (AMP)-Activated Protein Kinase-Nuclear Factor Kappa-B Pathway

The aim of the present research was to investigate the effects of irisin, a skeletal muscle-derived myokine, on spinal cord injury (SCI) in rats and explore the possible mechanisms. SCI model was constructed in male SD rats. The effects of irisin on SCI rats were assessed via behavior tests includin...

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Detalles Bibliográficos
Autores principales: Jiang, Xi, Shen, Zhihong, Chen, Jin, Wang, Chao, Gao, Zhan, Yu, Songling, Yu, Xuefeng, Chen, Lei, Xu, Lexing, Chen, Ziwei, Ni, Wenjuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701590/
https://www.ncbi.nlm.nih.gov/pubmed/33312127
http://dx.doi.org/10.3389/fphar.2020.582484