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Obeticholic acid attenuates human immunodeficiency virus/alcohol metabolism-induced pro-fibrotic activation in liver cells

BACKGROUND: The morbidity and mortality of human immunodeficiency virus (HIV)-infection is often associated with liver disease, which progresses slowly into severe liver dysfunction. There are multiple insults which exacerbate HIV-related liver injury, including HIV-associated dysregulation of lipid...

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Detalles Bibliográficos
Autores principales: New-Aaron, Moses, Ganesan, Murali, Dagur, Raghubendra Singh, Kharbanda, Kusum K, Poluektova, Larisa Y, Osna, Natalia A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701963/
https://www.ncbi.nlm.nih.gov/pubmed/33312422
http://dx.doi.org/10.4254/wjh.v12.i11.965