Determination of Configuration and Conformation of a Reserpine Derivative with Seven Stereogenic Centers Using Molecular Dynamics with RDC‐Derived Tensorial Constraints

NMR‐based determination of the configuration of complex molecules containing many stereocenters is often not possible using traditional NOE data and coupling patterns. Making use of residual dipolar couplings (RDCs), we were able to determine the relative configuration of a natural product containin...

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Detalles Bibliográficos
Autores principales: Sager, Emine, Tzvetkova, Pavleta, Gossert, Alvar D., Piechon, Philippe, Luy, Burkhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7702126/
https://www.ncbi.nlm.nih.gov/pubmed/32744785
http://dx.doi.org/10.1002/chem.202002642

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7702126/
https://www.ncbi.nlm.nih.gov/pubmed/32744785
http://dx.doi.org/10.1002/chem.202002642

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