‘Nur'turing tumor T cell tolerance and exhaustion: novel function for Nuclear Receptor Nur77 in immunity

The nuclear receptor Nur77 is expressed in a multitude of tissues, regulating cell differentiation and homeostasis. Dysregulation of Nur77 signaling is associated with cancer, cardiovascular disease, and disorders of the CNS. The role of Nur77 in T cells has been studied for almost 30 years now. The...

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Detalles Bibliográficos
Autores principales: Lith, Sanne C., van Os, Bram W., Seijkens, Tom T.P., de Vries, Carlie J.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Highlights
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7702156/
https://www.ncbi.nlm.nih.gov/pubmed/33063848
http://dx.doi.org/10.1002/eji.202048869

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7702156/
https://www.ncbi.nlm.nih.gov/pubmed/33063848
http://dx.doi.org/10.1002/eji.202048869

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