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ADAM10 mediates ectopic proximal tubule development and renal fibrosis through Notch signalling

Disturbed intrauterine development increases the risk of renal disease. Various studies have reported that Notch signalling plays a significant role in kidney development and kidney diseases. A disintegrin and metalloproteinase domain 10 (ADAM10), an upstream protease of the Notch pathway, is also r...

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Detalles Bibliográficos
Autores principales: Li, Bingjue, Zhu, Chaohong, Dong, Lihua, Qin, Jing, Xiang, Wenyu, Davidson, Alan J, Feng, Shi, Wang, Yucheng, Shen, Xiujin, Weng, Chunhua, Wang, Cuili, Zhu, Tingting, Teng, Lisha, Wang, Junwen, Englert, Christoph, Chen, Jianghua, Jiang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7702158/
https://www.ncbi.nlm.nih.gov/pubmed/32715474
http://dx.doi.org/10.1002/path.5517