Poldip2 mediates blood‐brain barrier disruption and cerebral edema by inducing AQP4 polarity loss in mouse bacterial meningitis model

BACKGROUND: Specific highly polarized aquaporin‐4 (AQP4) expression is reported to play a crucial role in blood‐brain barrier (BBB) integrity and brain water transport balance. The upregulation of polymerase δ‐interacting protein 2 (Poldip2) was involved in aggravating BBB disruption following ische...

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Detalles Bibliográficos
Autores principales: Gao, Meng, Lu, Weitian, Shu, Yue, Yang, Zhengyu, Sun, Shanquan, Xu, Jin, Gan, Shengwei, Zhu, Shujuan, Qiu, Guoping, Zhuo, Fei, Xu, Shiye, Wang, Yiying, Chen, Junhong, Wu, Xuan, Huang, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7702237/
https://www.ncbi.nlm.nih.gov/pubmed/32790044
http://dx.doi.org/10.1111/cns.13446

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7702237/
https://www.ncbi.nlm.nih.gov/pubmed/32790044
http://dx.doi.org/10.1111/cns.13446

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