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LEF1 Induces DHRS2 Gene Expression in Human Acute Leukemia Jurkat T-Cells

OBJECTIVE: T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive disease resulting from the accumulation of genetic changes that affect the development of T-cells. The precise role of lymphoid enhancer-binding factor 1 (LEF1) in T-ALL has been controversial since both overexpression and inact...

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Detalles Bibliográficos
Autores principales: Sırma Ekmekci, Sema, Emrence, Zeliha, Abacı, Neslihan, Sarıman, Melda, Salman, Burcu, Ekmekci, Cumhur Gökhan, Güleç, Çağrı
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7702649/
https://www.ncbi.nlm.nih.gov/pubmed/32586085
http://dx.doi.org/10.4274/tjh.galenos.2020.2020.0144