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Novel antibodies detect additional α-synuclein pathology in synucleinopathies: potential development for immunotherapy
BACKGROUND: Alpha-synuclein (α-Syn) aggregation is the primary characteristic of synucleinopathies including Parkinson’s disease (PD), dementia with Lewy bodies (DLB) and multiple system atrophy (MSA). Immunotherapy targeting α-Syn has shown promising results in animal models of the disease. This st...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7702704/ https://www.ncbi.nlm.nih.gov/pubmed/33256825 http://dx.doi.org/10.1186/s13195-020-00727-x |