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Novel antibodies detect additional α-synuclein pathology in synucleinopathies: potential development for immunotherapy

BACKGROUND: Alpha-synuclein (α-Syn) aggregation is the primary characteristic of synucleinopathies including Parkinson’s disease (PD), dementia with Lewy bodies (DLB) and multiple system atrophy (MSA). Immunotherapy targeting α-Syn has shown promising results in animal models of the disease. This st...

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Detalles Bibliográficos
Autores principales:	Nimmo, Jacqui T., Verma, Ajay, Dodart, Jean-Cosme, Wang, Chang Yi, Savistchenko, Jimmy, Melki, Ronald, Carare, Roxana O., Nicoll, James A. R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7702704/ https://www.ncbi.nlm.nih.gov/pubmed/33256825 http://dx.doi.org/10.1186/s13195-020-00727-x

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