Cargando…

Structure of human endo-α-1,2-mannosidase (MANEA), an antiviral host-glycosylation target

Mammalian protein N-linked glycosylation is critical for glycoprotein folding, quality control, trafficking, recognition, and function. N-linked glycans are synthesized from Glc(3)Man(9)GlcNAc(2) precursors that are trimmed and modified in the endoplasmic reticulum (ER) and Golgi apparatus by glycos...

Descripción completa

Detalles Bibliográficos
Autores principales: Sobala, Łukasz F., Fernandes, Pearl Z., Hakki, Zalihe, Thompson, Andrew J., Howe, Jonathon D., Hill, Michelle, Zitzmann, Nicole, Davies, Scott, Stamataki, Zania, Butters, Terry D., Alonzi, Dominic S., Williams, Spencer J., Davies, Gideon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7703563/
https://www.ncbi.nlm.nih.gov/pubmed/33154157
http://dx.doi.org/10.1073/pnas.2013620117