Folate System Gene Variant rs1801394 66A>G may have a Causal Role in Down Syndrome in the Eastern Indian Population

Down syndrome (DS) is associated with trisomy of the 21(st) chromosome in more than 95% cases. The extra chromosome mostly derives due to abnormal chromosomal segregation, i.e. non-disjunction, during meiosis. Earlier reports showed that abnormal folate metabolism can lead to DNA hypomethylation and...

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Detalles Bibliográficos
Autores principales: Chatterjee, Mahasweta, Saha, Tanusree, Maitra, Subhamita, Sinha, Swagata, Mukhopadhyay, Kanchan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Babol University of Medical Sciences 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7703665/
https://www.ncbi.nlm.nih.gov/pubmed/33274184
http://dx.doi.org/10.22088/IJMCM.BUMS.9.3.215

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7703665/
https://www.ncbi.nlm.nih.gov/pubmed/33274184
http://dx.doi.org/10.22088/IJMCM.BUMS.9.3.215

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