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Correlated cryogenic fluorescence microscopy and electron cryo-tomography shows that exogenous TRIM5α can form hexagonal lattices or autophagy aggregates in vivo

Members of the tripartite motif (TRIM) protein family have been shown to assemble into structures in both the nucleus and cytoplasm. One TRIM protein family member, TRIM5α, has been shown to form cytoplasmic bodies involved in restricting retroviruses such as HIV-1. Here we applied cryogenic correla...

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Detalles Bibliográficos
Autores principales: Carter, Stephen D., Mamede, João I., Hope, Thomas J., Jensen, Grant J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7703684/
https://www.ncbi.nlm.nih.gov/pubmed/33154161
http://dx.doi.org/10.1073/pnas.1920323117