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γ-TRIS: a graph-algorithm for comprehensive identification of vector genomic insertion sites

SUMMARY: Retroviruses and their vector derivatives integrate semi-randomly in the genome of host cells and are inherited by their progeny as stable genetic marks. The retrieval and mapping of the sequences flanking the virus-host DNA junctions allows the identification of insertion sites in gene the...

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Detalles Bibliográficos
Autores principales: Calabria, Andrea, Beretta, Stefano, Merelli, Ivan, Spinozzi, Giulio, Brasca, Stefano, Pirola, Yuri, Benedicenti, Fabrizio, Tenderini, Erika, Bonizzoni, Paola, Milanesi, Luciano, Montini, Eugenio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7703754/
https://www.ncbi.nlm.nih.gov/pubmed/31589304
http://dx.doi.org/10.1093/bioinformatics/btz747