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γ-TRIS: a graph-algorithm for comprehensive identification of vector genomic insertion sites
SUMMARY: Retroviruses and their vector derivatives integrate semi-randomly in the genome of host cells and are inherited by their progeny as stable genetic marks. The retrieval and mapping of the sequences flanking the virus-host DNA junctions allows the identification of insertion sites in gene the...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7703754/ https://www.ncbi.nlm.nih.gov/pubmed/31589304 http://dx.doi.org/10.1093/bioinformatics/btz747 |