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bayNorm: Bayesian gene expression recovery, imputation and normalization for single-cell RNA-sequencing data
MOTIVATION: Normalization of single-cell RNA-sequencing (scRNA-seq) data is a prerequisite to their interpretation. The marked technical variability, high amounts of missing observations and batch effect typical of scRNA-seq datasets make this task particularly challenging. There is a need for an ef...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7703772/ https://www.ncbi.nlm.nih.gov/pubmed/31584606 http://dx.doi.org/10.1093/bioinformatics/btz726 |