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SigHotSpotter: scRNA-seq-based computational tool to control cell subpopulation phenotypes for cellular rejuvenation strategies

SUMMARY: Single-cell RNA-sequencing is increasingly employed to characterize disease or ageing cell subpopulation phenotypes. Despite exponential increase in data generation, systematic identification of key regulatory factors for controlling cellular phenotype to enable cell rejuvenation in disease...

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Detalles Bibliográficos
Autores principales: Ravichandran, Srikanth, Hartmann, András, del Sol, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7703776/
https://www.ncbi.nlm.nih.gov/pubmed/31697324
http://dx.doi.org/10.1093/bioinformatics/btz827