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PRODIGY: personalized prioritization of driver genes

MOTIVATION: Evolution of cancer is driven by few somatic mutations that disrupt cellular processes, causing abnormal proliferation and tumor development, whereas most somatic mutations have no impact on progression. Distinguishing those mutated genes that drive tumorigenesis in a patient is a primar...

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Detalles Bibliográficos
Autores principales: Dinstag, Gal, Shamir, Ron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7703777/
https://www.ncbi.nlm.nih.gov/pubmed/31681944
http://dx.doi.org/10.1093/bioinformatics/btz815