SCSsim: an integrated tool for simulating single-cell genome sequencing data

MOTIVATION: Allele dropout (ADO) and unbalanced amplification of alleles are main technical issues of single-cell sequencing (SCS), and effectively emulating these issues is necessary for reliably benchmarking SCS-based bioinformatics tools. Unfortunately, currently available sequencing simulators a...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Zhenhua, Du, Fang, Sun, Xuehong, Li, Ao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Applications Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7703785/
https://www.ncbi.nlm.nih.gov/pubmed/31584615
http://dx.doi.org/10.1093/bioinformatics/btz713

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7703785/
https://www.ncbi.nlm.nih.gov/pubmed/31584615
http://dx.doi.org/10.1093/bioinformatics/btz713

Ejemplares similares