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Antimicrobial peptide activity is anticorrelated with lipid a leaflet affinity

The activity of antimicrobial peptides (AMPs) has significant bacterial species bias, the mechanisms of which are not fully understood. We employed single-molecule tracking to measure the affinity of three different AMPs to hybrid supported bilayers composed of lipid A extracted from four different...

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Detalles Bibliográficos
Autores principales: Nelson, Nathaniel, Opene, Belita, Ernst, Robert K., Schwartz, Daniel K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7703904/
https://www.ncbi.nlm.nih.gov/pubmed/33253275
http://dx.doi.org/10.1371/journal.pone.0242907