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Novel methods for epistasis detection in genome-wide association studies

More and more genome-wide association studies are being designed to uncover the full genetic basis of common diseases. Nonetheless, the resulting loci are often insufficient to fully recover the observed heritability. Epistasis, or gene-gene interaction, is one of many hypotheses put forward to expl...

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Detalles Bibliográficos
Autores principales: Slim, Lotfi, Chatelain, Clément, Azencott, Chloé-Agathe, Vert, Jean-Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7703915/
https://www.ncbi.nlm.nih.gov/pubmed/33253293
http://dx.doi.org/10.1371/journal.pone.0242927