Kalopanaxsaponin A induces reactive oxygen species mediated mitochondrial dysfunction and cell membrane destruction in Candida albicans

Candidiasis causes high morbidity and mortality among immunocompromised patients. Antifungal drug resistance and cytotoxicity highlight the need of effective antifungal therapeutics. In this study, we found that kalopanaxsaponin A (KPA), a triterpenoid saponin natural product, could inhibit the prol...

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Detalles Bibliográficos
Autores principales: Li, Ying, Shan, Mingzhu, Zhu, Yao, Yao, Huankai, Li, Hongchun, Gu, Bing, Zhu, Zuobin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7703927/
https://www.ncbi.nlm.nih.gov/pubmed/33253287
http://dx.doi.org/10.1371/journal.pone.0243066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7703927/
https://www.ncbi.nlm.nih.gov/pubmed/33253287
http://dx.doi.org/10.1371/journal.pone.0243066

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