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Component of nicotine-induced intracellular calcium elevation mediated through α3- and α5-containing nicotinic acetylcholine receptors are regulated by cyclic AMP in SH-SY 5Y cells

The pathway from the medial habenular nucleus to the interpeduncular nucleus, in which nicotinic acetylcholine receptor (nAChR) including the α3 and α5 subunits (α3 * and α5 * nAChRs) are expressed, is implicated in nicotine dependence. We investigated whether α3 * and α5 * nAChRs are regulated by c...

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Detalles Bibliográficos
Autores principales: Takahashi, Tamayo, Yoshida, Takayuki, Harada, Kana, Miyagi, Tatsuhiko, Hashimoto, Kouichi, Hide, Izumi, Tanaka, Shigeru, Irifune, Masahiro, Sakai, Norio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7703979/
https://www.ncbi.nlm.nih.gov/pubmed/33253222
http://dx.doi.org/10.1371/journal.pone.0242349