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Enhanced mitophagy in bronchial fibroblasts from severe asthmatic patients

BACKGROUND: Sub-epithelial fibrosis is a characteristic feature of airway remodeling in asthma which correlates with disease severity. Current asthma medications are ineffective in treating fibrosis. In this study, we aimed to investigate the mitochondrial phenotype in fibroblasts isolated from airw...

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Detalles Bibliográficos
Autores principales: Ramakrishnan, Rakhee K., Bajbouj, Khuloud, Hachim, Mahmood Y., Mogas, Andrea K., Mahboub, Bassam, Olivenstein, Ronald, Hamoudi, Rifat, Halwani, Rabih, Hamid, Qutayba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7704010/
https://www.ncbi.nlm.nih.gov/pubmed/33253229
http://dx.doi.org/10.1371/journal.pone.0242695