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Identification of the enzymes responsible for m(2,2)G and acp(3)U formation on cytosolic tRNA from insects and plants

Posttranscriptional modification of tRNA is critical for efficient protein translation and proper cell growth, and defects in tRNA modifications are often associated with human disease. Although most of the enzymes required for eukaryotic tRNA modifications are known, many of these enzymes have not...

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Detalles Bibliográficos
Autores principales: Funk, Holly M., Zhao, Ruoxia, Thomas, Maggie, Spigelmyer, Sarah M., Sebree, Nichlas J., Bales, Regan O., Burchett, Jamison B., Mamaril, Justen B., Limbach, Patrick A., Guy, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7704012/
https://www.ncbi.nlm.nih.gov/pubmed/33253256
http://dx.doi.org/10.1371/journal.pone.0242737