Molecular Dynamics Simulations on Interindividual Variability of Intestinal Fluids: Impact on Drug Solubilization

[Image: see text] Efficient delivery of oral drugs is dependent on their solubility in human intestinal fluid, a complex and dynamic fluid that contains colloidal structures composed of small molecules. These structures solubilize poorly water-soluble compounds, increasing their apparent solubility,...

Descripción completa

Detalles Bibliográficos
Autores principales: Parrow, Albin, Larsson, Per, Augustijns, Patrick, Bergström, Christel A. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7704030/
https://www.ncbi.nlm.nih.gov/pubmed/32787279
http://dx.doi.org/10.1021/acs.molpharmaceut.0c00588

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7704030/
https://www.ncbi.nlm.nih.gov/pubmed/32787279
http://dx.doi.org/10.1021/acs.molpharmaceut.0c00588

Ejemplares similares