Strong intracellular signal inactivation produces sharper and more robust signaling from cell membrane to nucleus

For a chemical signal to propagate across a cell, it must navigate a tortuous environment involving a variety of organelle barriers. In this work we study mathematical models for a basic chemical signal, the arrival times at the nuclear membrane of proteins that are activated at the cell membrane an...

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Detalles Bibliográficos
Autores principales: Ma, Jingwei, Do, Myan, Le Gros, Mark A., Peskin, Charles S., Larabell, Carolyn A., Mori, Yoichiro, Isaacson, Samuel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7704053/
https://www.ncbi.nlm.nih.gov/pubmed/33196636
http://dx.doi.org/10.1371/journal.pcbi.1008356

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7704053/
https://www.ncbi.nlm.nih.gov/pubmed/33196636
http://dx.doi.org/10.1371/journal.pcbi.1008356

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