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Regulation of alternative macrophage activation by MSCs derived hypoxic conditioned medium, via the TGF-β1/Smad3 pathway

Macrophages are re-educated and polarized in response to myocardial infarction (MI). The M2 anti-inflammatory phenotype is a known dominator of late stage MI. Mesenchymal stem cells (MSCs) represent a promising tool for cell therapy, particularly heart related diseases. In general, MSCs induce alter...

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Detalles Bibliográficos
Autores principales: Kim, Ran, Song, Byeong-Wook, Kim, Minji, Kim, Won Jung, Lee, Hee Won, Lee, Min Young, Kim, Jongmin, Chang, Woochul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7704222/
https://www.ncbi.nlm.nih.gov/pubmed/33050988
http://dx.doi.org/10.5483/BMBRep.2020.53.11.177