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Activation of pannexin-1 mediates triglyceride-induced macrophage cell death

The accumulation of triglycerides (TGs) in macrophages induces cell death, a risk factor in the pathogenesis of atherosclerosis. We had previously reported that TG-induced macrophage death is triggered by caspase-1 and -2, therefore we investigated the mechanism underlying this phenomenon. We found...

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Detalles Bibliográficos
Autores principales: Jung, Byung Chul, Kim, Sung Hoon, Lim, Jaewon, Kim, Yoon Suk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7704223/
https://www.ncbi.nlm.nih.gov/pubmed/33050989
http://dx.doi.org/10.5483/BMBRep.2020.53.11.179