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IFN-β signaling dampens microglia reactivity but does not prevent from light-induced retinal degeneration
Chronic activation of microglia is associated with retinal degeneration, which makes them a potential therapeutic target for retinal degenerative diseases including age-related macular degeneration (AMD). Interferon-beta (IFN-β) is a potent immune regulator, commonly used for the treatment of multip...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7704411/ https://www.ncbi.nlm.nih.gov/pubmed/33299932 http://dx.doi.org/10.1016/j.bbrep.2020.100866 |