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Characterization of human papillomavirus (HPV) 16 E6 seropositive individuals without HPV-associated malignancies after 10 years of follow-up in the UK Biobank

BACKGROUND: Antibodies against the HPV16 oncoprotein E6 are promising biomarkers for HPV16-driven oropharyngeal cancer (HPV16-OPC) due to their high sensitivity and specificity, and prospective manifestation. In previous studies, 0•7% of controls without HPV-associated malignancies were HPV16 E6 ser...

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Detalles Bibliográficos
Autores principales: Brenner, Nicole, Mentzer, Alexander J., Hill, Michael, Almond, Rachael, Allen, Naomi, Pawlita, Michael, Waterboer, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7704422/
https://www.ncbi.nlm.nih.gov/pubmed/33248371
http://dx.doi.org/10.1016/j.ebiom.2020.103123