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End-stage renal disease reduces the expression of drug-metabolizing cytochrome P450s

BACKGROUND: End-stage renal disease is an irreversible status of kidney dysfunction that reduces both renal and non-renal drug clearance. Accumulation of uremic toxins seems to modify the activities of drug-metabolizing cytochrome P450 (CYP) enzymes. The aim of the present work was to refine gene ex...

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Detalles Bibliográficos
Autores principales: Déri, Máté Tamás, Kiss, Ádám Ferenc, Tóth, Katalin, Paulik, József, Sárváry, Enikő, Kóbori, László, Monostory, Katalin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7704481/
https://www.ncbi.nlm.nih.gov/pubmed/32638224
http://dx.doi.org/10.1007/s43440-020-00127-w