Reduced reticulum–mitochondria Ca(2+) transfer is an early and reversible trigger of mitochondrial dysfunctions in diabetic cardiomyopathy

Type 2 diabetic cardiomyopathy features Ca(2+) signaling abnormalities, notably an altered mitochondrial Ca(2+) handling. We here aimed to study if it might be due to a dysregulation of either the whole Ca(2+) homeostasis, the reticulum–mitochondrial Ca(2+) coupling, and/or the mitochondrial Ca(2+)...

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Detalles Bibliográficos
Autores principales: Dia, Maya, Gomez, Ludovic, Thibault, Helene, Tessier, Nolwenn, Leon, Christelle, Chouabe, Christophe, Ducreux, Sylvie, Gallo-Bona, Noelle, Tubbs, Emily, Bendridi, Nadia, Chanon, Stephanie, Leray, Aymeric, Belmudes, Lucid, Couté, Yohann, Kurdi, Mazen, Ovize, Michel, Rieusset, Jennifer, Paillard, Melanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Contribution
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7704523/
https://www.ncbi.nlm.nih.gov/pubmed/33258101
http://dx.doi.org/10.1007/s00395-020-00835-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7704523/
https://www.ncbi.nlm.nih.gov/pubmed/33258101
http://dx.doi.org/10.1007/s00395-020-00835-7

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