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Cell type-specific 3D epigenomes in the developing human cortex

Lineage-specific epigenomic changes during human corticogenesis have remained elusive due to challenges with sample availability and tissue heterogeneity. For example, previous studies used single-cell RNA sequencing to identify at least nine major cell types and up to 26 distinct subtypes in the do...

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Detalles Bibliográficos
Autores principales: Song, Michael, Pebworth, Mark-Phillip, Yang, Xiaoyu, Abnousi, Armen, Fan, Changxu, Wen, Jia, Rosen, Jonathan D., Choudhary, Mayank NK, Cui, Xiekui, Jones, Ian R., Bergenholtz, Seth, Eze, Ugomma C., Juric, Ivan, Li, Bingkun, Maliskova, Lenka, Lee, Jerry, Liu, Weifang, Pollen, Alex A., Li, Yun, Wang, Ting, Hu, Ming, Kriegstein, Arnold R., Shen, Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7704572/
https://www.ncbi.nlm.nih.gov/pubmed/33057195
http://dx.doi.org/10.1038/s41586-020-2825-4