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TERT promoter alterations could provide a solution for Peto’s paradox in rodents

Cancer is a genetic disease caused by changes in gene expression resulting from somatic mutations and epigenetic changes. Although the probability of mutations is proportional with cell number and replication cycles, large bodied species do not develop cancer more frequently than smaller ones. This...

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Detalles Bibliográficos
Autores principales: Vedelek, Balázs, Maddali, Asha Kiran, Davenova, Nurgul, Vedelek, Viktor, Boros, Imre M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7704627/
https://www.ncbi.nlm.nih.gov/pubmed/33257697
http://dx.doi.org/10.1038/s41598-020-77648-0