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An original infection model identifies host lipoprotein import as a route for blood-brain barrier crossing

Pathogens able to cross the blood-brain barrier (BBB) induce long-term neurological sequelae and death. Understanding how neurotropic pathogens bypass this strong physiological barrier is a prerequisite to devise therapeutic strategies. Here we propose an innovative model of infection in the develop...

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Detalles Bibliográficos
Autores principales: Benmimoun, Billel, Papastefanaki, Florentia, Périchon, Bruno, Segklia, Katerina, Roby, Nicolas, Miriagou, Vivi, Schmitt, Christine, Dramsi, Shaynoor, Matsas, Rebecca, Spéder, Pauline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7704634/
https://www.ncbi.nlm.nih.gov/pubmed/33257684
http://dx.doi.org/10.1038/s41467-020-19826-2