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De novo induction of lineage plasticity from human prostate luminal epithelial cells by activated AKT1 and c-Myc
Neuroendocrine prostate cancer (NEPC) is an aggressive variant of prostate cancer that either develops de novo or arises from prostate adenocarcinoma as a result of treatment resistance. Although the prostate basal cells have been shown to directly generate tumor cells with neuroendocrine features w...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7704645/ https://www.ncbi.nlm.nih.gov/pubmed/33009488 http://dx.doi.org/10.1038/s41388-020-01487-6 |