Cargando…
De novo induction of lineage plasticity from human prostate luminal epithelial cells by activated AKT1 and c-Myc
Neuroendocrine prostate cancer (NEPC) is an aggressive variant of prostate cancer that either develops de novo or arises from prostate adenocarcinoma as a result of treatment resistance. Although the prostate basal cells have been shown to directly generate tumor cells with neuroendocrine features w...
Autores principales: | Kwon, Oh-Joon, Zhang, Li, Jia, Deyong, Zhou, Zhicheng, Li, Zhouyihan, Haffner, Michael, Lee, John K, True, Lawrence, Morrissey, Colm, Xin, Li |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7704645/ https://www.ncbi.nlm.nih.gov/pubmed/33009488 http://dx.doi.org/10.1038/s41388-020-01487-6 |
Ejemplares similares
-
Sox2 is necessary for androgen ablation-induced neuroendocrine differentiation from Pten null Sca-1(+) prostate luminal cells
por: Kwon, Oh-Joon, et al.
Publicado: (2020) -
The Role of Epigenetic Change in Therapy-Induced Neuroendocrine Prostate Cancer Lineage Plasticity
por: Storck, William K., et al.
Publicado: (2022) -
Stromal FOXF2 suppresses prostate cancer progression and metastasis by enhancing antitumor immunity
por: Jia, Deyong, et al.
Publicado: (2022) -
Lineage plasticity enables low-ER luminal tumors to evolve and gain basal-like traits
por: Mohamed, Gadisti Aisha, et al.
Publicado: (2023) -
MYC regulates ductal-neuroendocrine lineage plasticity in pancreatic ductal adenocarcinoma associated with poor outcome and chemoresistance
por: Farrell, Amy S., et al.
Publicado: (2017)