Conserved interactions required for inhibition of the main protease of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

The COVID-19 pandemic caused by the SARS-CoV-2 requires a fast development of antiviral drugs. SARS-CoV-2 viral main protease (Mpro, also called 3C‐like protease, 3CLpro) is a potential target for drug design. Crystal and co-crystal structures of the SARS-CoV-2 Mpro have been solved, enabling the ra...

Descripción completa

Detalles Bibliográficos
Autores principales: Shitrit, Alina, Zaidman, Daniel, Kalid, Ori, Bloch, Itai, Doron, Dvir, Yarnizky, Tali, Buch, Idit, Segev, Idan, Ben-Zeev, Efrat, Segev, Elad, Kobiler, Oren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7704658/
https://www.ncbi.nlm.nih.gov/pubmed/33257760
http://dx.doi.org/10.1038/s41598-020-77794-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7704658/
https://www.ncbi.nlm.nih.gov/pubmed/33257760
http://dx.doi.org/10.1038/s41598-020-77794-5

Ejemplares similares