Cargando…
Theophylline Dosing and Pharmacokinetics for Renal Protection in Neonates with Hypoxic Ischemic Encephalopathy Undergoing Therapeutic Hypothermia
BACKGROUND: Theophylline, a non-selective adenosine receptor antagonist, improves renal perfusion in the setting of hypoxia-ischemia and may offer therapeutic benefit in neonates with hypoxic ischemic encephalopathy (HIE) undergoing hypothermia. We evaluated the pharmacokinetics and dose-exposure re...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7704857/ https://www.ncbi.nlm.nih.gov/pubmed/32919393 http://dx.doi.org/10.1038/s41390-020-01140-8 |