Simultaneous profiling of chromatin accessibility and methylation on human cell lines with nanopore sequencing

Probing epigenetic features on DNA has tremendous potential to advance our understanding of the phased epigenome. In this study, we use nanopore sequencing to evaluate CpG methylation and chromatin accessibility simultaneously on long strands of DNA by applying GpC methyltransferase to exogenously l...

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Detalles Bibliográficos
Autores principales: Lee, Isac, Razaghi, Roham, Gilpatrick, Timothy, Molnar, Michael, Gershman, Ariel, Sadowski, Norah, Sedlazeck, Fritz J., Hansen, Kasper D., Simpson, Jared T., Timp, Winston
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7704922/
https://www.ncbi.nlm.nih.gov/pubmed/33230324
http://dx.doi.org/10.1038/s41592-020-01000-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7704922/
https://www.ncbi.nlm.nih.gov/pubmed/33230324
http://dx.doi.org/10.1038/s41592-020-01000-7

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