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Effect of the versatile bifunctional chelator AAZTA(5) on the radiometal labelling properties and the in vitro performance of a gastrin releasing peptide receptor antagonist

BACKGROUND: Gastrin Releasing Peptide receptor (GRPr)-based radioligands have shown great promise for diagnostic imaging of GRPr-positive cancers, such as prostate and breast. The present study aims at developing and evaluating a versatile GRPr-based probe for both PET/SPECT imaging as well as intra...

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Detalles Bibliográficos
Autores principales: Hofstetter, Michael, Moon, Euy Sung, D’Angelo, Fabio, Geissbühler, Lucien, Alberts, Ian, Afshar-Oromieh, Ali, Rösch, Frank, Rominger, Axel, Gourni, Eleni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7704979/
https://www.ncbi.nlm.nih.gov/pubmed/33258012
http://dx.doi.org/10.1186/s41181-020-00115-8