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The Role of HDAC6 in TDP-43-Induced Neurotoxicity and UPS Impairment

Transactive response DNA-binding protein 43 (TDP-43)-induced neurotoxicity is currently well recognized as a contributor to the pathology of amyotrophic lateral sclerosis (ALS), and the deposition of TDP-43 has been linked to other neurodegenerative diseases, such as frontotemporal lobar degeneratio...

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Detalles Bibliográficos
Autores principales: Lee, Shinrye, Kwon, Younghwi, Kim, Seyeon, Jo, Myungjin, Jeon, Yu-Mi, Cheon, Mookyung, Lee, Seongsoo, Kim, Sang Ryong, Kim, Kiyoung, Kim, Hyung-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705063/
https://www.ncbi.nlm.nih.gov/pubmed/33282865
http://dx.doi.org/10.3389/fcell.2020.581942