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Lung Epithelial TRPA1 Mediates Lipopolysaccharide-Induced Lung Inflammation in Bronchial Epithelial Cells and Mice

Toll-like receptor (TLR) 4 was originally thought to be the sole pattern recognition receptor for lipopolysaccharide (LPS). Transient receptor potential ankyrin 1 (TRPA1), a Ca(2+)-permeant channel, has been suggested as a non-TLR receptor membrane-bound sensor of LPS. We recently reported that TRPA...

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Detalles Bibliográficos
Autores principales: Ko, Hsin-Kuo, Lin, An-Hsuan, Perng, Diahn-Warng, Lee, Tzong-Shyuan, Kou, Yu Ru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705107/
https://www.ncbi.nlm.nih.gov/pubmed/33281629
http://dx.doi.org/10.3389/fphys.2020.596314