Current Evidence for a Bidirectional Loop Between the Lysosome and Alpha-Synuclein Proteoforms

Cumulative evidence collected in recent decades suggests that lysosomal dysfunction contributes to neurodegenerative diseases, especially if amyloid proteins are involved. Among these, alpha-synuclein (aSyn) that progressively accumulates and aggregates in Lewy bodies is undisputedly a main culprit...

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Detalles Bibliográficos
Autores principales: Wildburger, Norelle C., Hartke, Anna-Sophia, Schidlitzki, Alina, Richter, Franziska
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705175/
https://www.ncbi.nlm.nih.gov/pubmed/33282874
http://dx.doi.org/10.3389/fcell.2020.598446

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705175/
https://www.ncbi.nlm.nih.gov/pubmed/33282874
http://dx.doi.org/10.3389/fcell.2020.598446

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