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Probing Ligand-Receptor Interaction in Living Cells Using Force Measurements With Optical Tweezers
This work probes the binding kinetics of COOH-terminus of Clostridium perfringens enterotoxin (c-CPE) and claudin expressing MCF-7 cells using force spectroscopy with optical tweezers. c-CPE is of high biomedical interest due to its ability to specifically bind to claudin with high affinity as well...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705203/ https://www.ncbi.nlm.nih.gov/pubmed/33282853 http://dx.doi.org/10.3389/fbioe.2020.598459 |