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Probing Ligand-Receptor Interaction in Living Cells Using Force Measurements With Optical Tweezers

This work probes the binding kinetics of COOH-terminus of Clostridium perfringens enterotoxin (c-CPE) and claudin expressing MCF-7 cells using force spectroscopy with optical tweezers. c-CPE is of high biomedical interest due to its ability to specifically bind to claudin with high affinity as well...

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Detalles Bibliográficos
Autores principales:	Riesenberg, Carolin, Iriarte-Valdez, Christian Alejandro, Becker, Annegret, Dienerowitz, Maria, Heisterkamp, Alexander, Ngezahayo, Anaclet, Torres-Mapa, Maria Leilani
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705203/ https://www.ncbi.nlm.nih.gov/pubmed/33282853 http://dx.doi.org/10.3389/fbioe.2020.598459

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