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Calcium Oscillations in Pancreatic α-cells Rely on Noise and ATP-Driven Changes in Membrane Electrical Activity
In pancreatic α-cells, intracellular Ca(2+) ([Ca(2+)](i)) acts as a trigger for secretion of glucagon, a hormone that plays a key role in blood glucose homeostasis. Intracellular Ca(2+) dynamics in these cells are governed by the electrical activity of voltage-gated ion channels, among which ATP-sen...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705205/ https://www.ncbi.nlm.nih.gov/pubmed/33281631 http://dx.doi.org/10.3389/fphys.2020.602844 |