The Identification of a Novel Thiopurine S-Methyltransferase Allele, TPMT*45, in Korean Patient with Crohn’s Disease

Pediatric Crohn’s disease (CD) carries a higher genetic susceptibility and an increased risk of a more aggressive disease course than adult CD. Treatment of CD is based on immunomodulatory drugs, such as thiopurines. The enzyme mainly involved in drug metabolism is thiopurine S-methyltransferase (TP...

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Detalles Bibliográficos
Autores principales: Ha, Changhee, Kim, Eun Sil, Kwon, Yiyoung, Choe, Yon Ho, Kim, Mi Jin, Lee, Soo-Youn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705256/
https://www.ncbi.nlm.nih.gov/pubmed/33273844
http://dx.doi.org/10.2147/PGPM.S279446

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705256/
https://www.ncbi.nlm.nih.gov/pubmed/33273844
http://dx.doi.org/10.2147/PGPM.S279446

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