Effects of Tacrolimus and Other Immune Targeting Compounds on Binge-Like Ethanol Drinking in High Drinking in the Dark Mice

High Drinking in the Dark (HDID-1) mice represent a unique genetic risk model of binge-like drinking and a novel means of screening potential pharmacotherapies to treat alcohol use disorders (AUDs). We tested the effects of tacrolimus (0, 0.5, 1, and 2 mg/kg), sirolimus (0, 5, 10, and 20 mg/kg), pal...

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Detalles Bibliográficos
Autores principales: Grigsby, Kolter B, Savarese, Antonia M, Metten, Pamela, Mason, Barbara J, Blednov, Yuri A, Crabbe, John C, Ozburn, Angela R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Molecular Mechanisms of Alcohol Use Disorders
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705291/
https://www.ncbi.nlm.nih.gov/pubmed/33294845
http://dx.doi.org/10.1177/2633105520975412

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705291/
https://www.ncbi.nlm.nih.gov/pubmed/33294845
http://dx.doi.org/10.1177/2633105520975412

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