Chronic neuronal activation increases dynamic microtubules to enhance functional axon regeneration after dorsal root crush injury

After a dorsal root crush injury, centrally-projecting sensory axons fail to regenerate across the dorsal root entry zone (DREZ) to extend into the spinal cord. We find that chemogenetic activation of adult dorsal root ganglion (DRG) neurons improves axon growth on an in vitro model of the inhibitor...

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Detalles Bibliográficos
Autores principales: Wu, Di, Jin, Ying, Shapiro, Tatiana M., Hinduja, Abhishek, Baas, Peter W., Tom, Veronica J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705672/
https://www.ncbi.nlm.nih.gov/pubmed/33257677
http://dx.doi.org/10.1038/s41467-020-19914-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705672/
https://www.ncbi.nlm.nih.gov/pubmed/33257677
http://dx.doi.org/10.1038/s41467-020-19914-3

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